User blog comment:Red's Not Dead/BRING RED BACK? OR BRING RED BACK!/@comment-2222639-20101015013546

Revolver took place in the mid 1800's, like any typical Western game. By 1914, the end date of Red Dead Redemption, Red Harlow is likely very old or has died from age.

I'm perfectly fine with John Marston as a single protagonist, although the possibility of another Red game as a prequel to Redemption is possible.

There's also the possibility of one of Redemption's characters secretly being Red, such as Uncle, or Bo Schrim, etc.