Most of us know about Francis Sinclair, right? He’s a time traveller in RDR2 (We know that because of his clothes and accent, plus the rock carvings and his business card)
He has a weird birthmark on his face, and in GTA, the Epsilon Program (Parody of Scientology) has a website which shows what a descendant of Kraff (their God) might look like. The most prominent part of this image is a birthmark that is the same as Francis’s in RDR2.
Furthermore, the Program claims that the world is actually 157 years old (Which would mean that the world started in 1856, if we are talking about GTAV’s story.) Francis looks to be in his 40s. Francis might actually be born in 1856 and be the founder of the Epsilon Program, which would mean that they are part of the same universe...