I just love New Austin! It gives me the raw wild west feeling that the other states failed to give me. I also love hanging around in Tumbleweed, shooting up the Del-Lobo hideouts and riding through the country to enjoy the old vibes of RDR1.
New Hanover is great because of the Heartlands and Chapter 2 but Roanoke Ridge ruins it. Lemoyne has so much content which sure is great but sometimes also annoying. Ambarino's scenery is sooo great but there's nothing to do apart from hunting and enjoying the nature. West Elizabeth is overrated! I'm not the biggest fan of the Big Valley region and Great Plains/Tall Trees are done so much worse than in RDR1...