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Skin from a Buffalo, of very high value.
In-game description

Buffalo Skin is an animal item found in Red Dead Redemption. It can be sold to merchants and is considered an item of very high value.

Characteristics

This item can be obtained by skinning an American Buffalo in West Elizabeth. However, even after skinning the final buffalo on the plains, you may still find them in random encounters being chased by a man on horseback.

Note: prices listed on this page are based upon the player having neutral honor and playing the game on Normal difficulty. If the player has high honor, the selling price will be Increased by 50% everywhere except Thieves' Landing. Low Honor decreases selling price by 50% everywhere except Thieves' Landing. While playing the game on Hardcore difficulty, money is more scarce and the base, neutral honor price of each item will be slightly lower.


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