Doyle's Tavern is a bar situated in Saint Denis.
The tavern is used a number of times within the game's story, usually as a meeting point for the main characters.
A random encounter can occur, where the bartender asks the player help to take care of rat infestation in his bar.
Another random encounter can occur when prostitute offers services to the player. If they accept she will lead them outside of the bar where Italian mobsters are waiting to ambush them.