Listed below are the storyline missions in Red Dead Redemption 2. The narrative of Red Dead Redemption 2 spans four or five different territories and 109 different missions (94 story missions, as well as 15 "honor missions") which are separated in 6 chapters and a 2-part epilogue. Completing each unique mission tallies in the Progress Menu in the game and the Missions Module of the Social Club interface and counts towards 100% Completion.
Chapter 1: Colter
After a failed robbery, the gang have fled from Blackwater into the Grizzly Mountains, but a late spring storm has left them half frozen and starving. They hole up in an abandoned mining town to lick their wounds and await a break in the weather.
The gang got run of Valentine after an altercation with the railway magnate, Leviticus Cornwall, who has grown tired of having his trains robbed by gangs of outlaws. Afraid that the routes westwards were being watched by Pinkerton agents, the gang moved south and east and are now hiding at Clemens Cove, near the town of Rhodes.
If coming from Chapter 2 by completing "An American Pastoral Scene", players jump directly into "Advertising, The New American Art")
Further Questions of Female Suffrage branch (only after A Strange Kindness from Ch. 2)
Below are the 26 of the 31 stranger side-missions for Red Dead Redemption 2. "Brothers and Sisters, One and All", "Do Not Seek Absolution", "Help a Brother Out", "Money Lending and Other Sins" and "Of Men and Angels" are stranger missions as well, but they are also counted as "honor missions" and thus are included in the chapters above.
Request: Milkweed, Kentucky Bourbon, Peppermint, Hair Pomade and Skunk
Reward: Tornado Boots, Classic Frock Coat, Drifter Hat and Frontier Vest (unique items)
During part 2 of the epilogue, John becomes indebted to the bank. Even if the player acquires the indebted sum of $465 or more outside of the main missions, the money can't be used to pay off the debt and the player must instead complete the storyline missions that result in John making the payments.
The best time to trigger an item request (besides during missions and companion activities) is from noon to approximately the evening. This makes it easier as the gang members are not asleep or eating dinner despite some of them not being available after 12pm or after 3pm.
Due to Lenny's request being at night, it is best triggered at around 10pm as the gang members tend to stay up for a long time at night.