Oleander Sage is a plant that can be found and sold in Red Dead Redemption 2.


If consumed, the protagonist will vomit and lose a large amount of health. Eating 4 or 5 even with max health results in death. It is useful for manually causing a fail screen if a mission is glitched or broken.

Due to it being a poison, Oleander Sage is necessary to craft poisonous weapons, such as Poison Arrows and Poison Throwing Knives.


Oleander Sage shrubs can be identified by the thin leaves and small five petal pink flowers. The popular herb can be seen growing near the river banks of Bayou Nwa. This shrub is considered to be one of the most poisonous plants in America and should never be consumed. The cardiac glycoside poisons produced by this plant can be used to craft deadly poison.[1]


  • Lemoyne:
    • Macomb's End: Just west of the "n" in "End", on the river bank.
    • On the north bank of the Kamassa River, almost straight north from the docks at Caliga Hall.
    • To the east of the "N" in "Lemoyne", on the inside of the curve of the river.


  • Oleander Sage is based on the Oleander shrub (Nerium oleander), in real life. There is no existing sage species with the qualities or flower type shown by this "sage" in Redemption 2.
  • If the player decides to consume the plant they will suffer damage and vomit.


  1. In-game compendium entry
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