Established in 1844, this prison lies on a small island off Lemoyne's eastern shore.
The island is surrounded by watchtowers, each housing guards on look-out. Encircling the prison are many fields and barns, all of which serve as labor camps for the inmates. In the center sits the main prison itself, comprised of many small buildings, and larger ones. These structures are enclosed by a fortified wall. The penitentiary is segregated into two wards; a ward for males, and the other for females.
Events of Red Dead Redemption 2
Following the Van der Linde gang's failed heist of the Saint Denis bank, John Marston is captured and imprisoned at Sisika. Following the gang's return from Guarma, Arthur and Sadie begin planning a way to break him out.
Arthur flies above the prison in a hot air balloon, along with Arturo Bullard, in the hopes of locating John. The prison guards open fire on the balloon, forcing them to retreat to the mainland. Fortunately for them, they managed to spot John before being shot out of the sky.
Later, Sadie and Arthur take a rowboat to the island, and land on the island's western shore. They quickly kill the guard in one of the island's watchtowers, and spot who they presume is John. After defeating the guards patrolling the prisoners working in the fields, they realize that the man they believed to be John is not John. Swiftly, Arthur captures another guard and holds him hostage, forcing him to reveal that John is not working that day. The two, with the guard hostage, approach the entrance of the prison and demand an exchange. After getting John in the trade-off, they fight their way to the shore, enter in the boat, and row back to the mainland.
Red Dead Online
After the murder of Mr. LeClerk, the online protagonist is framed and wrongfully convicted of committing the crime. They are sent to Sisika Penitentiary, and are sentenced to six months of penal labor and eventual execution. A week before their planned execution, the protagonist is freed by Horley, when he and his men intercept the transport holding the protagonist.
- Heston Jamson - Prison Warden
- Logan Hagen - Deputy Warden
- Miliken - Guard
- Jenkins - Guard
- Jackson - Guard (mentioned)
- Benton - Guard (mentioned)
- Townsend - Guard (mentioned)
- Due west of the Penitentiary building itself, the Legendary Bullhead Catfish can be fished within the channel leading toward the mainland.