Tonics come in 32 varieties in Red Dead Redemption 2. Tonics restore health, stamina, and/or Dead Eye, but do not restore any Cores, except for some of the horse items. Craftable tonics require a campfire.
| Image | Name | Buy Sell | Effect | Acquisition | Recipe |
|---|---|---|---|---|---|
| Aged Pirate Rum | - | Consuming this will give you stamina experience. | Loot | |
| Ginseng Elixir | - | Consuming this will give you health experience. | Loot | |
| Valerian Root | - | Consuming this will give you Dead Eye experience. | Loot | |
| Moonshine | $2.25 $1.10 | Fully restores health and fortifies slightly, slightly damages health core. | Buy or loot Sold by Fences | |
| Opened Health Cure | - | Fully restores health. | Loot | |
| Health Cure | $2.50 $1.25 | Fully restores health and fortifies slightly. | Buy or loot Sold by General Stores | |
| Potent Health Cure | $4.50 $2.25 | Fully restores health and fortifies moderately. | Buy, loot or craft Sold by Doctors | 1x Alaskan Ginseng/American Ginseng + 1x Yarrow |
| Special Health Cure | - | Fully restores health and fortifies greatly. | Craft | 2x Alaskan Ginseng/American Ginseng + 2x Yarrow + 2x English Mace/Milkweed |
| Cocaine Gum | $5.00 | Fully restores stamina and fortifies slightly. Slightly damages stamina core. | Buy or loot Sold by General Stores and Doctors | |
| Opened Bitters | - | Fully restores stamina. | Loot | |
| Bitters | $3.00 $1.50 | Fully restores stamina and fortifies slightly. | Buy or loot Sold by General Stores and Doctors | |
| Potent Bitters | $5.00 $2.50 | Fully restores stamina and fortifies moderately. | Buy, loot or craft Sold by Doctors | 1x Hummingbird Sage/Desert Sage + 1x Burdock Root |
| Special Bitters | - | Fully restores stamina and fortifies greatly. | Craft | 2x Hummingbird Sage/Desert Sage + 2x Burdock Root + 2x Violet Snowdrop/Wild Feverfew |
| Chewing Tobacco | $6.00 | Fully restores Dead Eye and fortifies slightly. Slightly damages Dead Eye core. | Buy or loot Sold by General Stores and Doctors | |
| Opened Snake Oil | - | Fully restores Dead Eye. | Loot | |
| Snake Oil | $3.50 $1.75 | Fully restores Dead Eye and fortifies slightly. | Buy or loot Sold by General Stores and Doctors | |
| Potent Snake Oil | $5.50 $2.75 | Fully restores Dead Eye and fortifies moderately. | Buy, loot or craft Sold by Doctors | 1x Indian Tobacco |
| Special Snake Oil | - | Fully restores Dead Eye and fortifies greatly. | Craft | 2x Indian Tobacco + 2x Blackcurrant/Golden Currant/Prairie Poppy |
| Opened Miracle Tonic | - | Fully restores Health, Stamina and Dead Eye. | Loot | |
| Miracle Tonic | $4.00 $2.00 | Fully restores Health, Stamina and Dead Eye and fortifies slightly. | Buy or loot Sold by General Stores and Doctors | |
| Potent Miracle Tonic | $7.00 $3.50 | Fully restores Health, Stamina and Dead Eye and fortifies moderately. | Buy, loot or craft Sold by Doctors | 4x Indian Tobacco + 4x Alaskan Ginseng/American Ginseng + 4x Hummingbird Sage/Desert Sage |
| Special Miracle Tonic | - | Fully restores Health, Stamina and Dead Eye and fortifies greatly. | Craft | 6x Blackcurrant/Golden Currant + 6x Yarrow + 6x Burdock Root |
| Opened Horse Medicine | - | Fully restores Horse Health. | Loot | |
| Horse Medicine | $1.50 $0.75 | Fully restores Horse Health and fortifies slightly. | Buy or loot Sold by General Stores, Doctors and Stables | |
| Potent Horse Medicine | $3.00 $1.50 | Fully restores Horse Health and fortifies moderately. | Buy, loot or craft Sold by General Stores, Doctors and Stables | 1x Alaskan Ginseng/American Ginseng + 1x Common Bulrush |
| Special Horse Medicine | - | Fully restores Horse Health and fortifies greatly. | Craft | 2x Alaskan Ginseng/American Ginseng + 2x Common Bulrush + 2x Wild Carrot |
| Horse Stimulant | $2.50 $1.25 | Fully restores Horse stamina and fortifies slightly. | Buy or loot Sold by General Stores, Doctors and Stables | |
| Potent Horse Stimulant | $4.00 $2.00 | Fully restores Horse stamina and fortifies moderately. | Buy or loot Sold by General Stores, Doctors and Stables | 1x Hummingbird Sage/Desert Sage + 1x Common Bulrush |
| Special Horse Stimulant | - | Fully restores Horse stamina and fortifies greatly. | Craft | 2x Hummingbird Sage/Desert Sage + 2x Common Bulrush + 2x Wild Carrot |
| Horse Reviver | $9.50 $4.75 | Revives horse from severe injury and moderately restores its health. | Buy or loot Sold by General Stores, Doctors and Stables | |
| Special Horse Reviver | - | Revives horse from severe injury and yields a gold health Core for a day. | Craft | 2x Alaskan Ginseng/American Ginseng + 2x Wild Carrot + 2x Parasol Mushroom |
| Horse Meal | - | A decent meal for the horse. Fully restores all horse cores and yields gold cores for a day. | Craft - does not require campfire | 3x Blackcurrant/Golden Currant + 3x Beets + 3x Hay |
| Horse Ointment | - | Greatly restores horse health core and fully restores stamina core and yields a gold stamina core for a day. | Craft | 1x Hummingbird Sage/Desert Sage + 1x Common Bulrush + 1x Yarrow |
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